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Importance of Vitamin B6

One should have the information that vitamin b6 is actually a water-soluble vitamin which is a part of vitmain b complex group. Not only this pyridoxal phosphate which is a source of vitamin b6 is the active form and acting as cofactor in lots of reactions of amino acid metabolism like having transamination, deamination, and decarboxylation. So vitamin b6 helps in the enzymatic reaction supporting the release of glucose from glycogen in the body. One will also see that vitamin b6 called as pyridoxine for indicating its structural homology as pyridine. So all the three forms of vitamin b6 act as precursors of activated compounds called as pyridoxal 5′-phosphate, playing major role in number of essential enzymes of the human system.

The role of vitamin b6 shows its effectiveness for the treatment of PMS, PMDD, and clinical depression is still debatable. Not only this vitamin B6 is also experimented on schizophrenia and autism for showing its relevancy . There are several forms of vitamin b6 in the medical field suchas pyridoxine ,pyridoxine 5′-phosphate, pyridoxal, pyridoxal 5′-phosphate , pyridoxamine, pyridoxamine 5′-phosphate, 4-pyridoxic acid etc. The pyridoxal phosphate which is the metabolically active form of vitamin B6 is involve in various aspects of macronutrient metabolism, neurotransmitter synthesis, histamine synthesis, hemoglobin synthesis and function, and gene expression. Not only this vitamin b6 helps in serving as a coenzyme in many reactions helping in facilitating decarboxylation, transamination, racemization, elimination, replacement and beta-group interconversion reactions in the body. In human body the liver the place where vitamin B6 metabolism takeplace.

One will surprise to know that vitamin b6 helps in the conversion of tryptophan into niacin lowering vitamin b6 status in the body. Vitamin b6 keeps a major role in gluconeogenesis in the body. Also Pyridoxal phosphate helps in catalyzing transamination reactions which are important for providing amino acids to act as a substrate for gluconeogenesis. One can see that vitamin B6 is needed as coenzyme of glycogen phosphorylase which is that enzyme required for glycogenolysis for emerging along with Lipid metabolism . Not only this vitamin b6 act as an important component of enzymes facilitating biosynthesis of sphingolipids. The basic role of vitamin B6 is to remain as coenzyme in different enzymes in the body involving predominantly in metabolism. Its active form is converted into two other natural forms present in the food such as pyridoxal, pyridoxine and pyridoxamine etc.

Vitamin B6 shows its role in many metabolic processes like amino acid, glucose and lipid metabolism, neurotransmitter synthesis, histamine synthesis,hemoglobin synthesis and function, and gene expression etc.

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Question by Jennnny: Anyone with PMDD or Depression please help!!?
I’ve been dealing with pain and mood swings/depression for years. I have yet to be diagnosed and it is not only making me crazy, but everyone in my life crazy as well. I had an IUD put in 8 years ago. A few months afterwards, I started having labor like pains every month. I was told that I had IBS. I suffered for years and just dealt with it. Recently, I had a vaginal ultra sound, which showed that my IUD was in a little crooked. I am scheduled to have surgery to have it removed, and also to see if I maybe have endometriosis. My pain leads to severe mood swings and also depression. I literally feel as if I am going to lose my mind. I can’t deal with my kids, and my husband can’t stand me half the time. My friends even get annoyed with me. I get headaches on and off through out the month, my back hurts, I get muscle aches, and I don’t want to be bothered by anything, and sometimes don’t even want to get out of bed. I never feel good. When researching PMDD, I’ve discovered that I have every symptom listed, except for suicide. I don’t know anyone other than myself that has these problems. My family has a history of depression, but I feel as if mine only comes once a month, but lasts for 2weeks. It has interfered with my job and social life. I gain about 10lbs every months as well, and then lose it after my period. It is ridiculous how I have different sized clothes that I have to wear half of the month. I am always telling everyone how I am just a useless piece of crap for 2 weeks out of every month. What a way to live right. My doctor wants me to have a psyciatric evaluation after I have my surgery ruling everything else out, but I HATE drugs. I fear what I will have to take, and was just hoping that there was someone else out there who has the same problem and symptoms, who could maybe offer some advice and support. I would appreciate any input anyone has to offer. Thanks so much.

Best answer:

Answer by davelennv
Go see the psychiatrist. You hate drugs now, but after you get on them and they get into your system, I promise you you will feel like a new person.
I suffer from depression, anxiety, and panic attacks. I am on Prozac, and Klonopin and am a completely different person. More upbeat, outgoing, confident, etc.
If you need/want to talk, please do not hesitate to e-mail me

What do you think? Answer below!

Cymbalta Q&a

More Cymbalta questions please visit : DrugsFreeFAQ.com

What is the side affects of taking cymbalta and Xanax?
Can these taken together cause foot cramping Sleepiness. Everyone is different in response, so just don’t drive until you know how it affects you. Jiggle the doses around if it’s too much. About the foot cramps, I really doubt it. Just look the meds up on google and find side-effects for each…

What meds can i nick that don’t hold sexual side-effects approaching cymbalta does?
currently i’m on cymbalta, wellbutrin, and geodon and have been having erectile difficulties which is hurting my relationship a lil bit. does anyone know of any combination of meds i can take that wouldn’t enjoy the type of side-effects that there are now? – If the cymbalta is helping you,…

While taking cymbalta , I own be be have past its sell-by date the wall nightmares , is this run of the mill ?
i take cymbalta, and my doctor has told me that it can cause vivid dreams, but i have not experienced nightmares. it’s different for everyone, so chat with your doctor. I’d call the doctor and ask for another…

Why doesn’t cymbalta other work?
Is there something else that I can take when cymbalta isn’t enough to handle my depression and mood swings? There are tons medications on out there that can work for you more than Cymbalta has.There are so many more than satisfactory to list honestly. You need to talk to the one that out you on the Cymbalta about how it…

Why is cymbalta not for children lower than 18? ?
My question is. What does cymbalta do to children under 18 that makes the medicine not approved for them? – During clinical studies of antidepressants (including Cymbalta) and suicide, near was an increased risk of suicidal behavior in children and teenagers who took the medications. Although Cymbalta has not be approved for use…

Why prescribe cymbalta as a torment reliever for severe communal misery?
Because it can help calm down the pain receptors in your brain. Because it is a anti depressandt, lowers blood pressure, and pain reliver. Hope you feel better soon. In clinical studies, Cymbalta have shown to be effective in the treatment of pain related to osteoarthritis. Here’s an article: http://osteoarthritis.give…

Will ultram go and get rid of cymbalta debt symptoms?
I’ve been weaning off of cymbalta (with my physicians directions of course) and as part of the withdrawal symptoms i take these “brain zaps” that are really annoying. I’ve been prescribed percocet due to an ankle injury and it seems to get rid of the brain zaps. Tomorrow im going to the doctor and im…

Withdraw symptoms from cymbalta?
oh idk, google it. much the same as withdrawal from any other antidepressant.nausea, agitation, twitching, muscle pain, mental distortion, anxiety. all the route up to seizure activity and coma if the dose is high and stopped suddenly. Never a good hypothesis to go cold turkey off an antidepressant, always talk to a doctor roughly a taper. Source(s): RN…

Would cymbalta work>?
– Cymbalta helps my depression. It’s worth trying if you are depressed. Talk to your doctor about your symptoms. He/she may want to give Cymbalta a try. Good Luck. Depends on what you are using it for?

2 30mg of Cymbalta contained by place of 1 60mg?
I have a 30 day prescription of 30mg cymbalta, but my doctor told me to take the 60′s after a week. now I lone had 1 sample pack of the 60′s. So Can I just take 2 30′s to compensate? yes, you can bring 2 30mg capsules to make 60mgs. Source(s): RN

Can I find discount tickets for buy cymbalta?
Please is urgent. Check this one: http://searchalldeals.com/deals/search?c鈥? I don’t know where you’re from that the pharmacy accepts “tickets,” I’m surrounded by the US. Many times Psychiatrists have samples they can give to new patients. There are also discounted prices if you’re low income. – Free or low-cost medications provided by…

Can you bring back dignified past its sell-by date cymbalta?
Just answer the question, dont tell me i need help or etc, can you draw from high off cymbalta if you take it & your not prescribed it – No, if anything it ll make you a bit sick, the first few days i took 60mg of it, it made me sick, and…

Cymbalta cancel, anyone else suffer withdraw ? Anyway to win over it?
anyone else suffered withdraws from cymbalta Yes. Withdrawals are horrible from cymbalta. I went off cold turkey. I tried to wait it out but they last forever. After a week of vomiting i just went back on the pills. Very horrible addiction it is. They can last a month. With drawls near…

Cymbalta giving me unpromising nauseated intuition, vomiting, manager ache?
It is 60mg cymbalta. – What you are experiencing are transient side effects of Cymbalta. It’s not “normal” but it’s not uncommon either. It does go away over time as your body gets used to the medication. In the show time you can consider trying taking it with some food. …

Does cymbalta create you discern messed up?
I know cymbalta is an antidepressant but does it make you feel like xanax does? and it’s also for nerve distress so how does that make you feel. i’m nervous to start taking it though it’s been prescribed – I took Cymbalta for in the region of a week but I had such bad side effects…

Does risperdal serve next to concentration and research?
I take the newer version of risperdal (invega under new patent) and i know it help some with my concentration, but it could also be the cymbalta i take. It does make me drowsy/weak/sleepy though which helps to hold on to my mind from racing. risperdal is poison to the body and mind…I found much…

Has anybody else gone rotten cymbalta what side effects happen?
my face seems to bloat alot and my mood swings are bad does anybody know how to get ancient this i was on the cymbalta for almost a year it seems to have messed up my metablolism im not gaining counterbalance but cant loose it either even with exerxcise and diet…

Has anyone ben prescribed cymbalta for discomfort merely?
The thing is that chronic pain, chronic sleep deprivation and depression are part of the same cycle. That’s becaue chronic niggle keeps your brain from being able to regulate a number of neurochemicals, including seratonin. Seratonin is greatly responsible for both sleep and mood. Cymbalta is surrounded by a class of drugs called SNRI’s…

Has anyone else have increased appetite on Cymbalta? I enjoy be on it 20 days total.?
I take 30 mg daily, have I given it enough time for the side effects to fade or should I switch to another pill? I take it for PMDD. – yes, cymbalta can make you gain weight.. you can talk to your dr something like switching, but…

Has anyone ever taken cymbalta and did it work?
Yes! I’ve been taking cymbalta for 8 months and it took a week to start working but it help my neck, shoulder and hip pain. It was so bad I could just walk. Cymbalta worked for me and I have no side effects from it. I’d try it, it might work…

How long does it cart for diarrhea/dizzness cause by Cymbalta to budge away?
So i was on it for more then a week, i’m now off cymbalta, but i still own diarrhea/dizziness. Any clue on when it will go away. FLUSH IT DOWN WITH ORANGE JUICE AND PRUNE JUICE. ONLY TAKE LITTLE CYMBALTA AT A TIME SO YOUR STOMACH CAN GET USE TO IT. THAT…

I enjoy a side affect next to cymbalta?
This is kind of embarrasing of me to say. But I am finding it difficult to obtain and erection and ejaculate since I’ve been taking it. The doctor have given me 120mg/day. So far my anxiety has died down alot, but I don’t like the sexual side effect. What should I do? Well, 120…

I purely get support on cymbalta and it worked beforehand, but this second time its not. Help?
i was on cymbalta a while ago and it really helped. i stopped taking it because i started feeling better and didnt think i needed it anymore. very soon i;m severly depressed again and was put back on it and it doesnt really seem to be doing anything.